Bases moleculares, celulares y endocrinas de la pubertad y del desarrollo gonadal en lubina (Dicentrarchus labrax). Desarrollo de tecnologías ambientales, hormonales, y de manipulación génica para su control.



Dr.Silvia Zanuy Doste Departamento de Fisiología y Biotecnología de Peces IATS – CSIC
Ribera de Cabanes, s/n
12595 Torrelasal (Castellón)
Tel. 964 319500


Summary in english.

Puberty is the process whereby a sexually immature individual reaches the capability to reproduce. In the European sea bass, an economically important fish species for Mediterranean aquaculture, puberty is attained during the second and third year in males and females, respectively. The onset of puberty is generally linked to a retardation in somatic growth. In the particular case of sea bass males, this fact poses a problem since since they mature before reaching marketable size, thus resulting in important economic loses. For this reason, the ability to delay or even suppress puberty becomes an important advance for sea bass aquaculture. Sexual maturation consists in the development of mature gonads capable to produce male and female functional gametes thus giving rise to the offspring. For the proper progression of this process, a complex sequence of events involving the brain-pitutary-gonadal axis needs to be finely tuned.
In this context, gonadotropic hormones, FSH and LH, through their receptors have an essential role in vertebrate reproduction, triggering the onset of gametogenesis and gonadal growth. However, limited information about the proximate factors involved in the regulation of gametogenesis is currently available in fish. The aim of this project is to develop a model capable to explain the events that trigger the onset of puberty in the sea bass, as well as the casade of events that subsequently modulate gonadal development. For this purpose, molecular, biochemical, genetic and environmental approaches will be used.